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  • Bronopol CAS#52-51-7
  • Bronopol CAS#52-51-7
  • Bronopol CAS#52-51-7
  • Bronopol CAS#52-51-7
  • Bronopol CAS#52-51-7

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Bronopol CAS#52-51-7

Bronopol CAS#52-51-7

Basic Information

Effective Antimicrobial Agent：Bronopol acts as a preservative and biocide, preventing microbial growth in various formulations.


Versatile Usage：It can be incorporated into multiple products, including lubricants and cosmetic or pharmaceutical preparations.


Water-Soluble：Its solubility in water allows easy formulation and dispersion in aqueous products.


Stability in Formulations：Bronopol maintains antimicrobial efficacy over time, supporting long shelf-life of the products it protects.


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product description

Product Application of Bronopol CAS#52-51-7

Bronopol is a formaldehyde-releasing compound and has been identified as a potential allergen for dairy workers. In a reported case, bronopol contained in ultrasound lubricant jelly induced contact dermatitis in a veterinary surgeon.


Product Application of Bronopol CAS#52-51-7

Bronopol is used as an antimicrobial preservative at a concentration of 0.01–0.1% w/v, either alone or blended with other preservatives. It is applied in topical pharmaceuticals, cosmetics and personal care products, with a typical dosage of 0.02% w/v.

Product Information

Parameters


Melting point130-133 °C(lit.)
Boiling point358.0±42.0 °C(Predicted)
density2.0002 (rough estimate)
refractive index1.6200 (estimate)
Fp167°C
storage temp.Inert atmosphere,Room Temperature
solubilityH2O: soluble100mg/mL, clear, colorless to faintly yellow
pka12.02±0.10(Predicted)
formCrystals or Crystalline Powder
colorWhite to yellow
Odorodorless
Water Solubility25 g/100 mL (22 ºC)
Merck141447
BRN1705868
Stability:Stable. Hygroscopic. Incompatible with strong oxidizing agents, strong bases, strong reducing agents, acid chlorides and anhydrides, moisture.
Major Applicationagriculture
cleaning products
cosmetics
environmental
food and beverages
personal care
Cosmetics Ingredients FunctionsPRESERVATIVE
Cosmetic Ingredient Review (CIR)Bronopol (52-51-7)
InChI1S/C3H6BrNO4/c4-3(1-6,2-7)5(8)9/h6-7H,1-2H2
InChIKeyLVDKZNITIUWNER-UHFFFAOYSA-N
SMILESOCC(Br)(CO)[N+]([O-])=O
LogP1.150 (est)
CAS DataBase Reference52-51-7(CAS DataBase Reference)
NIST Chemistry ReferenceBronopol(52-51-7)
EPA Substance Registry SystemBronopol (52-51-7)


Safety Information


Hazard CodesXn,N
Risk Statements21/22-37/38-41-50
Safety Statements26-37/39-61-36/37/39
RIDADRUN 3241 4.1/PG 3
WGK Germany2
RTECSTY3385000
F4.2-8-9-21
TSCATSCA listed
HazardClass4.1
PackingGroupIII
HS Code29055999
Storage Class4.1B - Flammable solid hazardous materials
Hazard ClassificationsAcute Tox. 4 Dermal
Acute Tox. 4 Oral
Aquatic Acute 1
Aquatic Chronic 1
Eye Dam. 1
Skin Irrit. 2
STOT SE 3
Hazardous Substances Data52-51-7(Hazardous Substances Data)
ToxicityLD50 in mice, rats (mg/kg): 350, 400 orally (Croshaw)


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