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Fluconazole CAS#86386-73-4

Fluconazole CAS#86386-73-4

Basic Information

Broad-Spectrum Antifungal Activity:Fluconazole provides effective inhibition against a wide range of fungal pathogens, making it suitable for multiple antifungal applications.


Systemic Antifungal Efficacy:As a systemic antifungal agent, it delivers reliable therapeutic performance throughout the body for deep and systemic fungal infections.


Highly Selective Mechanism of Action:It selectively inhibits fungal cytochrome P-450-dependent enzymes, ensuring targeted antifungal activity with high specificity.


Potent Inhibition of Fungal Sterol Synthesis:Fluconazole strongly and specifically blocks fungal sterol biosynthesis, disrupting fungal cell membrane formation and preventing growth.


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product description

Product Description of Fluconazole CAS#86386-73-4

Fluconazole is an advanced triazole antifungal medication initially developed by Pfizer Pharmaceuticals in the United States. It offers broad-spectrum antifungal activity and is designed for systemic use. Fluconazole selectively targets and inhibits fungal cytochrome P-450-dependent enzymes, and it is also a powerful and specific inhibitor of fungal alcohol synthesis.

Product Application of Fluconazole CAS#86386-73-4

Fluconazole is a broad-spectrum triazole antifungal drug with an antibacterial spectrum similar to ketoconazole. It is long-acting, highly effective against deep fungal infections, and provides strong antifungal activity with good oral absorption. It is mainly used for the treatment of candidiasis and cryptococcosis, and is also effective for oropharyngeal candidiasis in cancer patients.

Product Information

Parameters


Melting point138-140°C
Boiling point579.8±60.0 °C(Predicted)
density1.05
Fp9℃
storage temp.2-8°C
solubilityDMSO: 5 mg/mL
formsolid
pkapKa 1.76±0.1(H2O t=24 I=0.1(NaCl)) (Uncertain)
colorWhite to Off-White
Water Solubility1g/L(temperature not stated)
Merck144122
BCS Class1,3
InChIInChI=1S/C13H12F2N6O/c14-10-1-2-11(12(15)3-10)13(22,4-20-8-16-6-18-20)5-21-9-17-7-19-21/h1-3,6-9,22H,4-5H2
InChIKeyRFHAOTPXVQNOHP-UHFFFAOYSA-N
SMILESC1(C=CC(F)=CC=1F)C(O)(CN1N=CN=C1)CN1N=CN=C1
CAS DataBase Reference86386-73-4(CAS DataBase Reference)


Safety Information


Hazard CodesXn,Xi,T,F
Risk Statements22-36/37/38-20/21/22-39/23/24/25-23/24/25-11
Safety Statements26-36-36/37/39-24/25-45-36/37-16-7
RIDADRUN1230 - class 3 - PG 2 - Methanol, solution
WGK Germany3
RTECSXZ4810000
HS Code29336990
Hazardous Substances Data86386-73-4(Hazardous Substances Data)


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