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  • Artemisinin CAS#63968-64-9
  • Artemisinin CAS#63968-64-9
  • Artemisinin CAS#63968-64-9
  • Artemisinin CAS#63968-64-9
  • Artemisinin CAS#63968-64-9

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Artemisinin CAS#63968-64-9

Artemisinin CAS#63968-64-9

Basic Information

Highly effective and fast-acting against malaria, with global efficacy over 90% in artemisinin-based combination therapies (ACT).


Strong and rapid killing effect on the erythrocytic stage of Plasmodium, quickly controlling clinical attacks and symptoms.


Broad-spectrum activity against multiple diseases, including chicken coccidiosis, swine eperythrozoonosis, toxoplasmosis, and various forms of malaria (vivax, malignant, cerebral, and chloroquine-resistant).


Low toxicity and additional therapeutic benefits, such as heat-clearing, summer-heat-relieving, and protozoon-killing properties.


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product description

Product Description of Artemisinin CAS#63968-64-9

Artemisinin is a peroxide-containing sesquiterpene lactone extracted from Artemisia annua. It features high potency, fast action and low toxicity.

Widely used in ACT therapy with over 90% curative rate globally, it rapidly eliminates plasmodium at erythrocytic stage to ease malaria symptoms. It also treats animal parasitic diseases and various fever-related disorders including drug-resistant malaria.


Product Application of Artemisinin CAS#63968-64-9

Extracted from sweet wormwood, artemisinin serves as a core antimalarial drug. It and its derivatives efficiently cure various malaria types including drug-resistant and cerebral malaria, featuring fast efficacy, low toxicity and no cross resistance with chloroquine.

Artemether exerts stronger inhibition on asexual plasmodium. Dihydroartemisinin boasts tenfold higher antimalarial activity and a low recurrence rate.
Apart from malaria, they are effective against parasites, lupus erythematosus and dengue fever. They also boost human immunity with no obvious damage to vital organs and few clinical side effects.

Product Information

Parameters


Melting point156-157 °C (lit.)
alpha76 º (c=0.5,MeOH)
Boiling point344.94°C (rough estimate)
density1.0984 (rough estimate)
refractive index75 ° (C=0.5, MeOH)
storage temp.-20°C
solubilitySoluble to 100mM in DMSO and to 75mM in ethanol
formWhite to off-white crystalline solid.
colorNeedles
optical activity[α]20/D +76°, c = 0.5 in methanol
Merck14817
Stability:Stable. Combustible. Incompatible with strong oxidizing agents, acids, acid chlorides, acid anhydrides. May absorb, and react with, carbon dioxide from the air.
InChIInChI=1S/C15H22O5/c1-8-4-5-11-9(2)12(16)17-13-15(11)10(8)6-7-14(3,18-13)19-20-15/h8-11,13H,4-7H2,1-3H3/t8-,9-,10+,11+,13-,14-,15-/m1/s1
InChIKeyBLUAFEHZUWYNDE-NNWCWBAJSA-N
SMILESO1[C@]23[C@@]4([H])O[C@@](C)(CC[C@@]2([H])[C@H](C)CC[C@@]3([H])[C@@H](C)C(=O)O4)O1
LogP2.9


Safety Information


Safety Statements22-24/25
WGK Germany2
RTECSKD4170000
HS Code29322985
ToxicityLD50 in mice (mg/kg): 5105 orally; 2800 i.m.; 1558 i.p. (Koch); LD50 in mice, rats (mg/kg): 4228, 5576 orally; 3840, 2571 i.m. (China Cooperative Research Group on Qinghaosu)


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