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Acetylsalicylic acid CAS#50-78-2

Acetylsalicylic acid CAS#50-78-2

Basic Information

Effective Anti-Inflammatory and Pain Relief: Aspirin acts as a nonsteroidal anti-inflammatory drug (NSAID), providing reliable reduction of inflammation and alleviation of pain in a wide range of conditions.


Anti-Thrombotic and Cardiovascular Protection: Aspirin helps prevent platelet aggregation, supporting cardiovascular health by reducing the risk of blood clot formation and contributing to the prevention of thrombotic events.


Reduction of Mortality from Heart Attack and Stroke: Regular use of aspirin has been shown to lower the mortality rate associated with myocardial infarction and ischemic stroke, making it a valuable intervention in high-risk patients.


Potential Cancer Risk Reduction: Emerging research indicates that aspirin may reduce the risk of developing colorectal cancer, highlighting its potential benefits beyond traditional cardiovascular and pain-relief applications.


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product description

Product Description of Acetylsalicylic Acid CAS#50-78-2

Aspirin, or acetylsalicylic acid, is a classic NSAID for anti-inflammation and pain relief. It inhibits platelet aggregation to prevent thrombosis, helping cut mortality from heart attack and stroke, and may also lower colorectal cancer risks.


Product Application of Acetylsalicylic Acid CAS#50-78-2

Acetylsalicylic acid is a key raw material for rodenticide intermediate synthesis, and hydrolyzes into salicylic acid and acetic acid. It is slightly soluble in water and easily soluble in organic solvents and alkaline solutions with possible decomposition.

Medically, it relieves fever, pain and rheumatism, facilitates uric acid excretion, inhibits platelet aggregation and treats biliary ascariasis.

It is also applied to durable outdoor structural parts and traffic markings for its stable protective performance.


Product Information

Parameters


Melting point134-136 °C (lit.)
Boiling point272.96°C (rough estimate)
density1.35
refractive index1.4500 (estimate)
Fp250 °C
storage temp.2-8°C
solubilityH2O: 10 mg/mL at 37 °C
formcrystalline
colorwhite
pka3.5(at 25℃)
biological sourcesynthetic
Water Solubility3.3 g/L (20 ºC)
ε(extinction coefficient)190 at 298nm in aqueous base at 1mM
409 at 231nm in aqueous base at 1mM
466 at 230nm in aqueous acid at 1mM
68 at 278nm in aqueous acid at 1mM
Merck14851
BRN779271
Exposure limitsACGIH: TWA 5 mg/m3
NIOSH: TWA 5 mg/m3
BCS Class3
Stability:Stable. Keep dry. Incompatible with strong oxidizing agents, strong bases, strong acids, various other compounds such as iodides, iron salts, quinine salts, etc.
InChIKeyBSYNRYMUTXBXSQ-UHFFFAOYSA-N
LogP1.19
CAS DataBase Reference50-78-2(CAS DataBase Reference)
NIST Chemistry ReferenceBenzoic acid, 2-(acetyloxy)-(50-78-2)
EPA Substance Registry SystemAspirin (50-78-2)


Safety Information


Hazard CodesXn
Risk Statements22-36/37/38
Safety Statements26-36/37/39
OEBB
OELTWA: 5 mg/m3
RIDADRUN 1851
WGK Germany1
RTECSVO0700000
TSCAYes
HazardClass6.1
PackingGroupIII
HS Code29182210
Hazardous Substances Data50-78-2(Hazardous Substances Data)
ToxicityLD50 orally in mice, rats: 1.1, 1.5 g/kg (Hart)


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