Products

Selected chemical raw materials supplied with consistent specifications, quality documentation and professional export support.

‹

›

Carbamazepine CAS#298-46-4

Carbamazepine CAS#298-46-4

Basic Information

Broad Antiepileptic Efficacy: Carbamazepine is effective in managing psychomotor seizures, grand mal seizures, localized seizures, and mixed seizure types, offering broad therapeutic coverage.


Superior Peripheral Neuropathy Support: Compared with phenytoin sodium, it provides better therapeutic performance in the treatment of peripheral neuropathy.


Effective Neuralgia Treatment: It is widely used for the management of trigeminal neuralgia and glossopharyngeal neuralgia, delivering reliable pain-relief benefits.


Versatile Clinical Applications: In addition to epilepsy treatment, carbamazepine can also be applied in arrhythmia and diabetes insipidus management, highlighting its multifunctional pharmaceutical value.


Can't Find The Product You Need?

Tell Us Your Product Requirements, Specifications And Target Industry, Our Professional Team Will Reply You Within 24 Hours.

Contact us

product description

Product Description of Carbamazepine CAS#298-46-4

Carbamazepine is a white or pale crystalline dibenzazepine antiepileptic agent. It works similarly to phenytoin sodium and is highly effective against psychomotor, generalized and partial seizures.

It shows superior effects on peripheral neuropathy, and is commonly used to relieve trigeminal and glossopharyngeal neuralgia. It is also applicable for arrhythmia and diabetes insipidus with wide clinical uses.

Product Application of Carbamazepine CAS#298-46-4

Carbamazepine is a dibenzazepine antiepileptic with effects similar to phenytoin sodium. It mainly treats psychomotor, generalized and partial seizures, and works better than phenytoin sodium for peripheral neuropathy, trigeminal and glossopharyngeal neuralgia. It is also used for arrhythmia and diabetes insipidus.
Its oral LD50 is 3750 mg/kg in mice and 4025 mg/kg in rats. Pharmacologically, it acts as a sodium channel inhibitor and binds to GABAA receptor benzodiazepine sites for medical and research use.


Product Information

Parameters


Melting point191-192 °C (lit.)
Boiling point378.73°C (rough estimate)
density1.1099 (rough estimate)
refractive index1.5906 (estimate)
Fp9℃
storage temp.2-8°C
solubility45% (w/v) aq 2-hydroxypropyl-β-cyclodextrin: soluble29mg/mL
formCrystals
pka13.94±0.20(Predicted)
colorAlmost white
Water Solubilitypract. insoluble
Merck141781
BCS Class2
LogP2.45
CAS DataBase Reference298-46-4(CAS DataBase Reference)
NIST Chemistry ReferenceCarbamazepine(298-46-4)
EPA Substance Registry System5H-Dibenz[b,f]azepine-5-carboxamide (298-46-4)


Safety Information


Hazard CodesXn,T,F
Risk Statements42/43-22-20/21/22-39/23/24/25-23/24/25-11
Safety Statements37-24-22-36/37/39-36-45-36/37-16
RIDADRUN1230 - class 3 - PG 2 - Methanol, solution
WGK Germany2
RTECSHN8225000
HS Code29339900
Hazardous Substances Data298-46-4(Hazardous Substances Data)
ToxicityLD50 orally in mice, rats: 3750, 4025 mg/kg (Stenger, Roulet)


Factory Showcase

详情-工厂

Shipping And Transportation

详情-物流

FAQ

Are you a manufacturer or a trading company?
Shandong Honghuida Chemical Co., Ltd. is a chemical product supplier and export company. We maintain long-term partnerships with reputable domestic manufacturers to provide customers with reliable chemical supplies and export services.

 

What are your main products?
We supply a wide range of chemical products, including basic chemical raw materials, fine chemicals, organic solvents, chemical intermediates, coating additives, plastic additives, and water treatment chemicals. Please contact our sales team for specific products, specifications, and availability.

 

Can you provide samples?
Samples are available for selected products. Sample and shipping costs depend on the product, quantity, and destination. Sample fees may be deducted from a subsequent commercial order upon agreement.

 

What is your minimum order quantity?
The minimum order quantity depends on the product, purity, packaging, and shipping method. Small trial orders are generally accepted. Please contact our sales team for details.

 

How can I get a quotation?
Please provide the product name, required specification or purity, quantity, packaging requirements, destination port, and preferred Incoterm. We will provide a quotation as soon as possible.

Contact Us

Submit

Related Recommendations