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Ibuprofen CAS#15687-27-1

Ibuprofen CAS#15687-27-1

Basic Information

Comprehensive Pain Relief:Ibuprofen effectively alleviates various types of pain, including headaches, muscle aches, and joint discomfort, making it a reliable analgesic for everyday use.


Strong Anti-inflammatory Effect:It reduces inflammation in the body, providing therapeutic benefits for conditions such as arthritis and rheumatic disorders.


Fever-lowering Capability:As an antipyretic, ibuprofen helps to reduce elevated body temperature, supporting its use in managing fever-related symptoms, though it is less frequently used for this purpose compared to paracetamol and aspirin.


Widely Trusted and Well-tolerated:With minimal adverse reactions, ibuprofen has gained global popularity and is recognized as one of the best-selling over-the-counter medications, considered alongside aspirin and paracetamol as a core product in antipyretic and analgesic treatments.


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product description

Product Description of Ibuprofen CAS#15687-27-1

Ibuprofen is a classic non-steroidal anti-inflammatory drug with analgesic, anti-inflammatory and antipyretic effects and mild side effects.
As one of the three mainstream fever and pain relievers together with aspirin and paracetamol, it is a popular over-the-counter medicine worldwide. It is mainly used for pain relief and rheumatism treatment domestically, and less commonly used for cold-related fever.


Product Application of Ibuprofen CAS#15687-27-1

Ibuprofen exerts anti-inflammatory, analgesic and antipyretic effects. Though slightly less potent than aspirin and phenylbutazone for rheumatism, it is widely used for rheumatoid arthritis, osteoarthritis, ankylosing spondylitis and neuritis.
It inhibits prostaglandin synthase and cyclooxygenase, preferentially suppressing COX-1 over COX-2 to achieve its pharmacological effects.


Product Information

Parameters


Melting point77-78 °C
Boiling point157 °C (4 mmHg)
alpha[α]D20 -1~+1°(c=1,C2H5OH)
density1.0364 (rough estimate)
refractive index1.5500 (estimate)
Fp9℃
storage temp.2-8°C
solubilityPractically insoluble in water, freely soluble in acetone, in methanol and in methylene chloride. It dissolves in dilute solutions of alkali hydroxides and carbonates.
pkapKa 4.45± 0.04(H2O,t = 25±0.5,I=0.15(KCl))(Approximate)
formCrystalline Powder
colorwhite to off-white
biological sourcesynthetic (organic)
Water Solubilityinsoluble
Merck144881
BCS Class2
Stability:Stable. Combustible. Incompatible with strong oxidizing agents.
InChIKeyHEFNNWSXXWATRW-UHFFFAOYSA-N
LogP3.97
CAS DataBase Reference15687-27-1(CAS DataBase Reference)
NIST Chemistry ReferenceIbuprofen(15687-27-1)
EPA Substance Registry SystemBenzeneacetic acid, .alpha.-methyl-4-(2-methylpropyl)- (15687-27-1)
Hazard CodesXn
Risk Statements22-63-51/53-39/23/24/25-23/24/25-11
Safety Statements36-61-36/37-45-16-7
HS Code29163920
Hazardous Substances Data15687-27-1(Hazardous Substances Data)
ToxicityLD50 in male mice, rats (mg/kg): 495, 626 i.p.; 1255, 1050 orally (Orzalesi)


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