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  • Loratadine CAS#79794-75-5
  • Loratadine CAS#79794-75-5
  • Loratadine CAS#79794-75-5
  • Loratadine CAS#79794-75-5
  • Loratadine CAS#79794-75-5

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Loratadine CAS#79794-75-5

Loratadine CAS#79794-75-5

Basic Information

Fast-acting and Long-lasting Relief：Loratadine provides rapid onset of action with prolonged antihistamine effects, ensuring sustained symptom control.


Non-sedating and Hormone-free：As a second-generation antihistamine, it does not contain hormones and has no significant central nervous system inhibitory effects.


Effective Allergy Symptom Control：It relieves symptoms of allergic rhinitis, such as sneezing, runny nose, and nasal itching, as well as eye irritation and skin allergies like urticaria.


Safe and Well-tolerated：Lacks significant anticholinergic effects, and toxicological studies show no mutagenic or teratogenic risks in animals.


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product description

Product Description of Loratadine CAS#79794-75-5

Loratadine is a second-generation long-acting tricyclic antihistamine for anti-allergy use. It acts fast powerfully without hormones, and is metabolized into more potent desloratadine in vivo.

It competitively blocks histamine H1 receptors to ease allergic symptoms, with few anticholinergic and sedative effects. It relieves allergic rhinitis and chronic urticaria symptoms. Animal tests prove it has no mutagenic or teratogenic risks.


Product Application of Loratadine CAS#79794-75-5

Loratadine is a highly selective antihistamine for peripheral H1 receptors, providing strong and long-lasting effects. It is used in the treatment of allergic conditions such as allergic rhinitis.

As a nationally classified Class II antiallergic drug, it is applied to relieve both nasal and non-nasal symptoms associated with seasonal allergic rhinitis, as well as to alleviate symptoms of chronic urticaria.


Product Information

Parameters


Melting point134-136°C
Boiling point531.3±50.0 °C(Predicted)
density1.261±0.06 g/cm3(Predicted)
RTECSTM6129200
storage temp.2-8°C
solubilityDMSO: 26 mg/mL, soluble
formpowder
pka4.27±0.20(Predicted)
colorwhite
Water SolubilityIt is soluble in DMSO (50 mg/ml), ethanol (77 mg/ml at 25°C), water (<1 mg/ml at 25°C), chloroform, and methanol.
Merck145578
BCS Class2
Stability:Stable, but may be heat sensitive - refrigerate. Incompatible with strong oxidizing agents.
InChIKeyJCCNYMKQOSZNPW-UHFFFAOYSA-N
CAS DataBase Reference79794-75-5(CAS DataBase Reference)
EPA Substance Registry System1-Piperidinecarboxylic acid, 4-(8-chloro-5,6-dihydro-11H-benzo[5,6]cyclohepta[1,2-b]pyridin-11-ylidene)-, ethyl ester (79794-75-5)
Hazard CodesXi
Risk Statements36/37/38
Safety Statements22-24/25-36-26
RIDADR3077
WGK Germany2
HS Code29333990
Hazardous Substances Data79794-75-5(Hazardous Substances Data)


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