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Streptomycin sulfate CAS#3810-74-0

Streptomycin sulfate CAS#3810-74-0

Basic Information

Proven Anti-Tuberculosis Efficacy:Streptomycin sulfate is the first chemotherapy antibiotic with a confirmed therapeutic effect against tuberculosis, offering reliable clinical value.


Powerful Bactericidal Action:It acts directly on bacterial ribosomes to inhibit protein synthesis, resulting in strong bactericidal activity.


High Effectiveness with Low Toxicity:Recognized as one of the most effective and least toxic antibiotics derived from Streptomyces for extra-gastrointestinal use.


Targeted Activity Against Extracellular TB Bacteria:Particularly effective against extracellular and cavitary tuberculosis bacteria, making it highly suitable for tuberculosis treatment applications.



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product description

Product Description of Streptomycin sulfate CAS#3810-74-0

Streptomycin sulfate is an antibiotic from Streptomyces griseus and the first effective anti-tuberculosis drug. Given via intramuscular injection, it is suitable for parenteral use with low toxicity. It kills bacteria by inhibiting ribosomal protein synthesis and mainly acts on extracellular tubercle bacilli.


Product Application of Streptomycin sulfate CAS#3810-74-0

Streptomycin sulfate inhibits most Gram-positive and Gram-negative bacteria, especially various Gram-negative strains. As a first-line anti-tuberculosis agent, it suppresses tubercle bacilli obviously at low doses and kills them at higher doses. It barely penetrates cells and mainly targets extracellular mycobacteria, working better on multiplying bacteria. Its bactericidal effect rises with concentration and peaks at pH 7.8.

Product Information

Parameters


Melting point>185°C (dec.)
alpha-79~-88°(20℃/D)(c=1,H2O)(calculated on the dried basis)
density1.2302 (rough estimate)
refractive index-85 ° (C=1, H2O)
storage temp.2-8°C
solubilityH2O: 0.1 g/mL, clear
formpowder
colorwhite to off-white
PHpH (100g/l, 25℃) : 4.5~7.0
Water Solubility>=0.01 g/100 mL at 18 ºC
Merck148826
BRN3894995
Specific Activity≥720IU/g (dry basis)
Stability:Stable. Incompatible with strong oxidizing agents.
InChIKeyQTENRWWVYAAPBI-YZTFXSNBSA-N
LogP-1.523 (est)
CAS DataBase Reference3810-74-0
EPA Substance Registry SystemStreptomycin sulfate (3810-74-0)


Safety Information


Hazard CodesXn,Xi
Risk Statements22-36/37/38-63-42/43
Safety Statements26-36-36/37-45-22-60
WGK Germany3
RTECSWK4990000
F3
TSCAYes
HS Code29412000


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