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Sinsenoside Rb1 CAS#41753-43-9

Sinsenoside Rb1 CAS#41753-43-9

Basic Information

Major Active Component of American Ginseng:Ginsenoside Rb1 is the principal bioactive constituent of American ginseng, ensuring high functional value.


Proven Anti-Aging Activity:Demonstrated anti-aging effects at both cellular and animal levels, supporting skin and overall vitality.


Enhances Hyaluronic Acid Synthesis:Its key metabolite 20GPPD increases HAS2 expression via ERK and AKT signaling, promoting hyaluronic acid production in human keratinocytes.


Advanced Cellular Signaling Activation:Activates ERK and AKT pathways in a dose-dependent manner, contributing to skin regeneration and anti-aging performance.


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product description

Product Description of Ginsenoside Rb1 CAS#41753-43-9

Ginsenoside Rb1 is a glycosylated protopanaxadiol (PPD)–type ginsenoside containing two sugar moieties attached at C-3 and two at C-20, and it represents the principal active component of American ginseng. Research has demonstrated that ginsenoside Rb1 exhibits anti-aging effects at both the cellular and animal levels.

Its main metabolite, 20-O-β-D-glucopyranosyl-20(S)-protopanaxadiol (20GPPD), has been shown in vitro to enhance HAS2 expression by activating ERK and AKT phosphorylation pathways in human keratinocytes in a dose-dependent manner.


Product Application of Ginsenoside Rb1 CAS#41753-43-9

Ginsenoside Rb1 is a major bioactive constituent of Panax ginseng that enhances neurotransmitter release by regulating synapsin phosphorylation through a cAMP-dependent protein kinase pathway. It has also been reported to exhibit immunostimulatory and anticancer activities.


Product Information

Parameters


Melting point197.5°C
Boiling point766.35°C (rough estimate)
density1.0971 (rough estimate)
refractive index1.6500 (estimate)
storage temp.2-8°C
solubilitymethanol: soluble9.80 - 10.20 mg/mL, clear, colorless to faintly yellow
pka12.85±0.70(Predicted)
formSolid
colorOff-White to Pale Beige
biological sourceplant root (Panax ginseng)
Stability:Hygroscopic
InChIKeyGZYPWOGIYAIIPV-VOKNSFSUNA-N
LogP2.900 (est)
CAS DataBase Reference41753-43-9(CAS DataBase Reference)


Safety Information


Hazard CodesXn,Xi,T,F
Risk Statements20/21/22-39/23/24/25-23/24/25-11
Safety Statements26-36-45-36/37-16-7
WGK Germany3
RTECSLZ5856000
HS Code29389090
Toxicityoms-rat-ipr 50 mg/kg CPBTAL 24,2400,76


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