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Methylprednisolone CAS#83-43-2

Methylprednisolone CAS#83-43-2

Basic Information

Powerful Anti-Inflammatory Effect:Methylprednisolone exhibits strong anti-inflammatory properties, making it highly effective in reducing inflammation associated with various medical conditions.


Immunomodulatory and Anti-Allergic Properties:It helps regulate the immune system and alleviates allergic reactions, supporting treatment of autoimmune and hypersensitivity disorders.


Wide Range of Clinical Applications:This glucocorticoid is used for emergency treatment of critical illnesses and for managing endocrine disorders, rheumatic and collagen diseases, skin conditions, ophthalmic diseases, gastrointestinal disorders, and blood-related illnesses.


Supportive in Complex Therapies:Methylprednisolone is effective in treating leukemia, shock, cerebral edema, neuritis, myelitis, and in preventing chemotherapy-induced vomiting, demonstrating versatility in critical and supportive care.



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product description

Products Description of Methylprednisolone CAS#83-43-2

Methylprednisolone (CAS#83-43-2) is a synthetic glucocorticoid with medium potency. It is highly valued in the medical field for its strong anti-inflammatory, immunomodulatory, and anti-allergic effects.

As a glucocorticoid medication, methylprednisolone is used for emergency treatment of critical conditions. It is also applied in managing endocrine disorders, rheumatic and collagen diseases, skin conditions, allergic reactions, ophthalmic disorders, gastrointestinal diseases, blood disorders, leukemia, shock, cerebral edema, neuritis, myelitis, and in preventing chemotherapy-induced vomiting.


Product Application of Methylprednisolone CAS#83-43-2

Methylprednisolone (CAS#83-43-2), a medium-potency glucocorticoid, exhibits anti-inflammatory, immunosuppressive, and anti-allergic effects. Clinically, it is used for acute flare-ups of rheumatic and immune-related conditions such as rheumatoid arthritis, acute exacerbations of bronchial asthma and other respiratory diseases, as well as ulcerative colitis and other digestive system disorders.


Product Information

Parameters


Melting point228-237°C (dec.)
alphaD20 +83° (dioxane)
Boiling point423.47°C (rough estimate)
density1.0868 (rough estimate)
refractive index82 ° (C=1, Dioxane)
storage temp.0-6°C
solubilitychloroform/methanol (9:1): 50 mg/mL, clear, faintly yellow
pka12.46±0.70(Predicted)
formSolid
colorWhite to Off-White
Water Solubility0.12g/L(25 ºC)
Merck146111
BRN2340300
BCS Class2 or 4?
InChIKeyVHRSUDSXCMQTMA-PJHHCJLFSA-N
CAS DataBase Reference83-43-2(CAS DataBase Reference)
NIST Chemistry Reference1,4-Pregnadiene-3,20-dione, 11beta,17alpha,21-trihydroxy-6alpha-methyl-(83-43-2)
EPA Substance Registry SystemPregna-1,4-diene-3,20-dione, 11,17,21-trihydroxy-6-methyl-, (6.alpha.,11.beta.)- (83-43-2)


Safety Information


Hazard CodesXi
Risk Statements36/37/38
Safety Statements22-36-26
WGK Germany2
RTECSTU4146000
F39744
HS Code2937290000
Hazardous Substances Data83-43-2(Hazardous Substances Data)









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